Alzheimer's, the dreaded disease! Could it be prevented? What information did researchers get and what is the link between Alzheimer's and the hormone of happiness!
The way you can find out if you do Alzheimer's. The technique can even help prevent the terrible illness.
A technique to detect the first signs of Parkinson's disease, which could help prevent and even prevent this condition, is closer to reality after a team of British scientists announced it took a step in that direction, a study published Thursday, quoted by AFP.
Early detection of Parkinson's disease is the primary focus of scientists studying this neurodegenerative condition, the second most common after Alzheimer's disease, Agerpres writes.
The treatments currently used in Parkinson's work on symptoms (tremor, motor disorders, sleep problems …), but do not heal the disease that begins some years before the first signs are visible, making it very difficult to diagnose.
Parkinson's is characterized by degeneration of dopamine neurons, which produce dopamine, a neurotransmitter essential to control body movements.
But a study published Thursday in the journal Lancet Neurology suggests that the early stages of the disease could be associated with a deterioration of the serotonin production system in the brain. This neurotransmitter interferes in particular in the regulation of mood and sleep.
Over time, researchers hope to identify early-risk individuals who are likely to develop Parkinson's.
"Early detection of changes in serotonin production could pave the way for developing new therapies to prevent and even prevent Parkinson's disease," said Professor Marios Politis, principal investigator at King's College London and funded by the Lily Foundation Safra.
To reach this conclusion, researchers analyzed 14 patients carrying a very rare genetic mutation (in the SNCA gene), which makes the risk of developing Parkinson's disease quasi-safe, according to the Press Association.
These patients were recruited in the northern Peloponnese peninsula of Greece, where this rare mutation occurred, as well as in Italy where they migrated.
Half of these patients already had physical symptoms of Parkinson's disease, and the other half had no such signs.
Also included in the study were 65 Parkinson's patients who did not have that genetic mutation and 25 non-afflicted participants.
All subjects underwent very good brain examinations.
After comparing all the data, it turned out that the degradation of the serotonin production system started in patients with Parkinson's disease long before the first symptoms appeared and before the dopamine production system was in turn affected.
Although the results were considered "encouraging" by scientists not involved in this study, they stressed that research has some limitations. First, the reduced number of volunteers predisposed genetically to Parkinson's disease. "More extensive studies could confirm these results," said Professor Derek Hill of University College London.
Another limitation, emphasized by the authors of the research, is that the imaging technique used is very costly and is not widespread, which does not allow generalization as a detection tool.